St. John’s Wort—A Non-Ototoxic Anti-Depressant
by Neil Bauman, Ph.D.
A man wrote:
I read an article on Dr. Jeffrey Dach’s website referring to the natural mood improving qualities of St. John’s Wort ["Beating Depression Naturally"], which also should have little or no side-effects when taking the recommended daily dosage (anywhere from 300mg-900mg).
I have been feeling “down” for the last year and a half, and thought I’d give it a try (mostly due to my hearing loss and adjusting to the new me). I also suffer from severe tinnitus and recruitment.
My question is this: “Is St. John’s Wort a non-ototoxic drug/herb? Is it safe to take?” I want to improve my mood, and would prefer to find a natural method; but don’t want to make my hearing loss any worse.
Here’s the scoop. Numerous studies have shown that St. John’s Wort is at least as effective as prescription drugs in treating mild to moderate cases of depression. (Just make sure it says on the label, “standardized to 0.3% (or 0.5%) Hypericin”. Hypericin is the active ingredient. If its not standardized to that amount, you don’t have a clue what you are really getting, and are likely just wasting your money.)
St. John’s Wort really works. My wife takes it as needed and has never had any ototoxic (or other) side effects like she had with prescription drugs. I know a number of others that have had the same experience.
Now for the really good news. St. John’s Wort is not known to be ototoxic in the least. So you can take it for as long as you need to without fear of causing hearing loss, aggravating your tinnitus, making your hyperacusis worse or wrecking your balance.
I’ve suggested to a good number of people that they ask their doctors to switch them to St. John’s Wort rather than the ototoxic prescription drugs they originally took in order to prevent further ototoxic damage to their ears.
However, don’t just start taking St. John’s Wort on your own. It is always wise to run this past your doctor because St. John’s Wort is known to interact with various medications. You don’t want to cause problems due to interactions between St. John’s Wort and any other medications you might be taking.
To learn which drugs and herbs are (or can be) ototoxic, see “Ototoxic Drugs Exposed“. This book contains information on the ototoxicity of 763 drugs, 30 herbs and 148 chemicals.









